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Article

Association between COMT Val158Met and psychiatric disorders: A comprehensive meta-analysis.

American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics - 1 Mar 2018

Taylor Steven

Abstract excerpt

Catechol-O-methyltransferase (COMT) Val158Met is widely regarded as potentially important for understanding the genetic etiology of many different psychiatric disorders. The present study appears to be the first comprehensive meta-analysis of COMT genetic association studies to cover all psychiatric disorders for which there were available data, published in any language, and with an emphasis on investigating...

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Identifiers

PMID: 28608575
DOI: 10.1002/ajmg.b.32556

Genes

COMT

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Related research

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Association between COMT Val158Met and psychiatric disorders: A comprehensive meta-analysis.PMID 28608575Read ↗

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Role of the COMT gene Val158Met polymorphism in mental disorders: a review.Semantic proximity Read ↗

Association of the catechol-O-methyltransferase val158met polymorphism and anxiety-related traits: a meta-analysis.Semantic proximity Read ↗

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Association between a functional catechol O-methyltransferase gene polymorphism and schizophrenia: meta-analysis of case-control and family-based studies.Semantic proximity Read ↗

Meta-Analysis of the COMT Val158Met Polymorphism in Major Depressive Disorder: Effect of Ethnicity.Semantic proximity Read ↗

A novel protein isoform of catechol O-methyltransferase (COMT): brain expression analysis in schizophrenia and bipolar disorder and effect of Val158Met genotype.Semantic proximity Read ↗

Attention-deficit/hyperactivity disorder phenotype is influenced by a functional catechol-O-methyltransferase variant.Semantic proximity Read ↗

Differential association of the COMT Val158Met polymorphism with clinical phenotypes in schizophrenia and bipolar disorder.Semantic proximity Read ↗

Meta-analysis of COMT val158met in panic disorder: ethnic heterogeneity and gender specificity.Semantic proximity Read ↗

Catechol-O-methyltransferase gene Val/Met functional polymorphism and risk of schizophrenia: a large-scale association study plus meta-analysis.Semantic proximity Read ↗

The met(158) allele of catechol-O-methyltransferase (COMT) is associated with obsessive-compulsive disorder in men: case-control study and meta-analysis.Semantic proximity Read ↗

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