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Article

Genetic predictors of glucocorticoid-induced hypertension in children with acute lymphoblastic leukemia.

Pharmacogenetics and genomics - 1 Jun 2008

Kamdem Landry K, Hamilton Leo, Cheng Cheng, Liu Wei, Yang Wenjian, Johnson Julie A, Pui Ching-Hon, Relling Mary V

Abstract excerpt

OBJECTIVE: Glucocorticoids are used universally in the remission induction therapy for acute lymphoblastic leukemia (ALL). One of the adverse effects of glucocorticoids is hypertension. Our aim was to define the frequency of and clinical and genetic risk factors for steroid-induced hypertension. METHODS: We determined the genotypes for 203 candidate polymorphisms in genes previously linked to hypertension or to...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 18496130
DOI: 10.1097/FPC.0b013e3282fc5801

Genes

ALPL
APOB
BGLAP
CNTNAP2
CRHR1
LEPR
NTAN1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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