Article
Methylenetetrahydrofolate reductase gene polymorphisms: association with risk for pediatric acute lymphoblastic leukemia in north Indians.
Leukemia & lymphoma - 1 May 2010
Sood Swati, Das Reena, Trehan Amita, Ahluwalia Jasmina, Sachdeva Man Updesh, Varma Neelam, Bansal Deepak, Marwaha Ram Kumar
Abstract excerpt
Genetic polymorphisms in the methylenetetrahydrofolate reductase (MTHFR) gene have been associated with the development of acute leukemias and various malignancies. We conducted a case-control study in 95 north Indian children with acute lymphoblastic leukemia (ALL) and 255 controls, to investiga...
Topics
- Adolescent
- Case-Control Studies
- Child
- Child, Preschool
- Female
- Genetic Predisposition to Disease
- Genotype
- Humans
- India
- Infant
- Male
- Methylenetetrahydrofolate Reductase (NADPH2)
- Polymerase Chain Reaction
- Polymorphism, Restriction Fragment Length