Article
Aberrant beta-catenin expression and adenomatous polyposis coli gene mutation in ameloblastoma and odontogenic carcinoma.
Oral oncology - 1 Feb 2009
Siriwardena B S M S, Kudo Y, Ogawa I, Tilakaratne W M, Takata T
Abstract excerpt
The Wnt pathway is involved in carcinogenesis and three regulatory genes of the Wnt pathway, APC (adenomatous polyposis coli), beta-catenin and Axin are frequently mutated in some primary human cancers. This study was conducted to clarify the relation of beta-catenin accumulation and the mutation of the CTNNB1 (beta-catenin) gene with the mutation of APC gene in the process of development of odontogenic tumors...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.