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Article

Mutations in components of the Wnt signaling pathway in adenoid cystic carcinoma.

Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc - 1 Dec 2004

Daa Tsutomu, Kashima Kenji, Kaku Naomi, Suzuki Masashi, Yokoyama Shigeo

Abstract excerpt

The Wnt signaling pathway is essential for normal development and organogenesis. However, inappropriate activation of Wnt signaling, which results in the nuclear translocation of beta-catenin, is associated with the development of various types of neoplasm. In this study, we investigated possible mutations in the genes for components of this pathway, namely, CTNNB1 (the gene for beta-catenin), AXIN1, and APC, in...

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Share to Adenomatous Polyposis Coli Protein
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Carcinoma, Adenoid Cystic

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Source

Identifiers

PMID: 15195113
DOI: 10.1038/modpathol.3800209

Genes

CTNNB1
APC
AXIN1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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