Article
The role of the adenomatous polyposis coli (APC) in oral squamous cell carcinoma.
Oral oncology - 1 Jan 2012
Pérez-Sayáns Mario, Suárez-Peñaranda José Manuel, Herranz-Carnero Michel, Gayoso-Diz Pilar, Barros-Angueira Francisco, Gándara-Rey José Manuel, García-García Abel
Abstract excerpt
The main cause of death in oral squamous cell carcinomas (OSCC) is metastasis. Intercellular adhesion is mediated by a family of glycoproteins called cadherins and other molecules like catenins and APC (adenomatous polyposis coli) among other. The WNT (wingless-type) gene family is a group of genes, key signaling pathway for embryonic development and oncogenesis. The goal of this paper is to describe the role of...
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