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Article

[Roles of beta-catenin overexpression and adenomatous polyposis coli mutation in head and neck cancer].

Nihon Jibiinkoka Gakkai kaiho - 1 Jun 2003

Takei Shin, Ueno Yumi, Yoda Junichi, Tamura Shinji, Hotomi Muneki, Fujihara Keiji, Kuki Kiyonori, Yamanaka Noboru

Abstract excerpt

Beta-catenin is an undercoat protein of cadherin, a cellular adhesion molecule. Beta-catenin also functions as a transcriptional activator downstream of the Wnt signaling pathway. Intracellular beta-catenin is regulated by the formation of a complex with APC (adenomatous polyposis coli) protein. The activation of this pathway by stabilization with beta-catenin has been shown to be an important step in the...

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Source

Identifiers

PMID: 12872724
DOI: 10.3950/jibiinkoka.106.692

Genes

APC

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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