Article
Beta-catenin mutations are frequent in calcifying odontogenic cysts, but rare in ameloblastomas.
The American journal of pathology - 1 Nov 2003
Sekine Shigeki, Sato Sunao, Takata Takashi, Fukuda Yasuo, Ishida Takeshi, Kishino Mitsunobu, Shibata Tatsuhiro, Kanai Yae, Hirohashi Setsuo
Abstract excerpt
We have reported previously that alterations to beta-catenin occur frequently in adamantinomatous craniopharyngioma. Based on its histological resemblance to some odontogenic tumors, we suspected the presence of common genetic alterations among these tumors. To address this issue, 11 cases of calcifying odontogenic cyst (COC) and 20 cases of ameloblastoma were investigated for the presence of beta-catenin...
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