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Article

Expression and mutation pattern of β-catenin and adenomatous polyposis coli in colorectal cancer patients.

Archives of medical research - 1 Jan 2015

Abdelmaksoud-Damak Rania, Miladi-Abdennadher Imen, Triki Mouna, Khabir Abdelmajid, Charfi Slim, Ayadi Lobna, Frikha Mounir, Sellami-Boudawara Tahia, Mokdad-Gargouri Raja

Abstract excerpt

BACKGROUND AND AIMS: β-Catenin and adenomatous polyposis coli (APC) are major components of the Wnt pathway. This study aimed to investigate the expression of β-catenin and APC in tumors and lymph nodes in colorectal cancer (CRC) patients and the mutational spectrum of the genes coding these proteins. METHODS: Expression of APC and β-catenin was examined in 124 tumors and 41 lymph nodes. Exon 3 of CTNNB1 and the...

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Source

Identifiers

PMID: 25660336
DOI: 10.1016/j.arcmed.2015.01.001

Genes

APC
CTNNB1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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