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Article

Beta-catenin accumulation and mutation of the CTNNB1 gene in hepatoblastoma.

Genes, chromosomes & cancer - 1 Aug 1999

Bläker H, Hofmann W J, Rieker R J, Penzel R, Graf M, Otto H F

Abstract excerpt

Hepatoblastoma is a rare malignant tumor of the liver that occurs in children at an average age of 2 to 3 years. Epidemiologic studies have shown an increased frequency of this tumor type in families affected by adenomatous polyposis coli. In addition to the epidemiologic data, molecular genetic studies suggest that inactivation of the APC tumor suppressor may be involved in hepatoblastoma tumorigenesis. A major...

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Source

Identifiers

PMID: 10398436

Genes

APC
CTNNB1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Beta-catenin accumulation and mutation of the CTNNB1 gene in hepatoblastoma.PMID 10398436Read ↗

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Expression and mutation pattern of β-catenin and adenomatous polyposis coli in colorectal cancer patients.Semantic proximity Read ↗

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