Article
HLA-A*2402-restricted HIV-1-specific cytotoxic T lymphocytes and escape mutation after ART with structured treatment interruptions.
Microbes and infection - 1 May 2008
Tanuma Junko, Fujiwara Mamoru, Teruya Katsuji, Matsuoka Saori, Yamanaka Hikaru, Gatanaga Hiroyuki, Tachikawa Natsuo, Kikuchi Yoshimi, Takiguchi Masafumi, Oka Shinichi
Abstract excerpt
Although a limited duration of immune activation of structured treatment interruptions (STIs) has been reported, the immune escape mechanism during STIs remains obscure. We therefore investigated the role of three immunodominant cytotoxic T lymphocyte (epitopes) in 12 HLA-A*2402-positive patients participating longitudinally during the clinical study of early antiretroviral treatment (ART) with five series of...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
