Article
Determinants of human immunodeficiency virus type 1 escape from the primary CD8+ cytotoxic T lymphocyte response.
The Journal of experimental medicine - 15 Nov 2004
Jones Nicola A, Wei Xiping, Flower Darren R, Wong Mailee, Michor Franziska, Saag Michael S, Hahn Beatrice H, Nowak Martin A, Shaw George M, Borrow Persephone
Abstract excerpt
CD8+ cytotoxic T lymphocytes (CTLs) play an important role in containment of virus replication in primary human immunodeficiency virus (HIV) infection. HIV's ability to mutate to escape from CTL pressure is increasingly recognized; but comprehensive studies of escape from the CD8 T cell response...
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