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Article

Emergence of drug-resistant HIV-1 variants in patients undergoing structured treatment interruptions.

AIDS (London, England) - 22 Nov 2002

Schweighardt Becky, Ortiz Gabriel M, Grant Robert M, Wellons Melissa, Miralles G Diego, Kostrikis Leondios G, Bartlett John A, Nixon Douglas F

Abstract excerpt

We report the emergence of drug-resistant viral mutations in chronically HIV-infected individual undergoing structured treatment interruptions (STI). THe protease mutations K101E and K103N were detected at the end of the second or third STI. We concluded that the repeated abrupt termination and resumption of certain antiretroviral drug regimens during STI therapy may lead to the development of drug resistance in...

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Identifiers

PMID: 12441810
DOI: 10.1097/00002030-200211220-00018

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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