Article
Immune escape mutations detected within HIV-1 epitopes associated with viral control during treatment interruption.
Journal of acquired immune deficiency syndromes (1999) - 1 Jan 2010
Schweighardt Becky, Wrin Terri, Meiklejohn Duncan A, Spotts Gerald, Petropoulos Christos J, Nixon Douglas F, Hecht Frederick M
Abstract excerpt
We analyzed immune responses in chronically HIV-infected individuals who took part in a treatment interruption (TI) trial designed for patients who initiated antiretroviral therapy within 6 months of seroconversion. In the 2 subjects who exhibited the best viral control, we detected CD8(+) T-cell...
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