Article
Mutations of the MYH gene do not substantially contribute to the risk of breast cancer.
Breast cancer research and treatment - 1 Apr 2009
Beiner Mario E, Zhang William W, Zhang Shiyu, Gallinger Steven, Sun Ping, Narod Steven A
Abstract excerpt
PURPOSE: To explore whether or not there is an association between the presence of either of the germline mutations in the MutY human homologue (MYH) gene (Y165C and G382D) and the risk of breast cancer. METHODS: 691 breast cancer patients and 812 healthy controls were genotyped for the MYH Y165C and G382D mutations. The frequencies of heterozygotes, homozygotes and compound heterozygotes were compared for the...
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