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Article

Exploring the Role of the MUTYH Gene in Breast, Ovarian and Endometrial Cancer.

Genes - 26 Apr 2024

Lintas Carla, Canalis Benedetta, Azzarà Alessia, Sabarese Giovanna, Perrone Giuseppe, Gurrieri Fiorella

Abstract excerpt

BACKGROUND: MUTYH germline monoallelic variants have been detected in a number of patients affected by breast/ovarian cancer or endometrial cancer, suggesting a potential susceptibility role, though their significance remains elusive since the disease mechanism is normally recessive. Hence, the aim of this research was to explore the hypothesis that a second hit could have arisen in the other allele in the tumor...

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Source

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Identifiers

PMID: 38790183
DOI: 10.3390/genes15050554
PMCID: PMC11120896

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026.

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Exploring the Role of the MUTYH Gene in Breast, Ovarian and Endometrial Cancer.PMID 38790183Read ↗

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