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Article

Germline mutations in the MYH gene in Swedish familial and sporadic colorectal cancer.

Genetic testing - 1 Jan 2005

Zhou X-L, Djureinovic T, Werelius B, Lindmark G, Sun X-F, Lindblom A

Abstract excerpt

Biallelic germline mutations in the base excision repair gene MYH have been shown to predispose to a proportion of multiple colorectal adenomas and cancer. To evaluate the contribution of MYH mutations to non- FAP, non-HNPCC familial colorectal cancer, 84 unrelated Swedish individuals affected with colorectal cancer from such families were screened for germline mutations in the coding sequence of the gene. None...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 15943555
DOI: 10.1089/gte.2005.9.147

Genes

FAP

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Germline mutations in the MYH gene in Swedish familial and sporadic colorectal cancer.PMID 15943555Read ↗

Biallelic germline mutations in MYH predispose to multiple colorectal adenoma and somatic G:C-->T:A mutations.Semantic proximity Read ↗

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Identification of MYH mutation carriers in colorectal cancer: a multicenter, case-control, population-based study.Semantic proximity Read ↗

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Germline MYH mutations in a clinic-based series of Canadian multiple colorectal adenoma patients.Semantic proximity Read ↗

Prevalence of the Y165C, G382D and 1395delGGA germline mutations of the <i>MYH</i> gene in Italian patients with adenomatous polyposis coli and colorectal adenomasSemantic proximity Read ↗

The thorough screening of the MUTYH gene in a large French cohort of sporadic colorectal cancers.Semantic proximity Read ↗

Role of MYH polymorphisms in sporadic colorectal cancer in China: a case-control, population-based study.Semantic proximity Read ↗

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