Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

MYH Y165C and G382D mutations in hepatocellular carcinoma and cholangiocarcinoma patients.

Journal of cancer research and clinical oncology - 1 Mar 2006

Baudhuin Linnea M, Roberts Lewis R, Enders Felicity T B, Swanson Russell L, Mettler Teresa A, Aderca Ileana, Stadheim Linda M, Highsmith W Edward

Abstract excerpt

PURPOSE: Production of reactive oxygen species (ROS) during chronic inflammation has been implicated in the progression of liver diseases and carcinogenesis. Subjects with inflammatory liver disease and one non-functional allele of the base excision repair gene, MYH, may be more susceptible to progression to cancer due to MYH haploinsufficiency in repairing oxidative damage caused by ROS. Here, we investigated...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Bile Duct Neoplasms
Share to Bile Ducts, Intrahepatic

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Carcinoma, Hepatocellular

Share to Cholangiocarcinoma

Share to DNA Glycosylases

Share to DNA Repair

Share to Liver Neoplasms

Share to Polymorphism, Restriction Fragment Length

Source

Identifiers

PMID: 16292541
DOI: 10.1007/s00432-005-0056-6

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

MYH Y165C and G382D mutations in hepatocellular carcinoma and cholangiocarcinoma patients.PMID 16292541Read ↗

MYH rs3219476 and rs3219472 polymorphisms and risk of cholangiocarcinoma.Semantic proximity Read ↗

Association between biallelic and monoallelic germline MYH gene mutations and colorectal cancer risk.Semantic proximity Read ↗

A common mutation of the MYH gene is associated with increased DNA oxidation and age-related diseases.Semantic proximity Read ↗

Role of MYH polymorphisms in sporadic colorectal cancer in China: a case-control, population-based study.Semantic proximity Read ↗

Identification of MYH mutation carriers in colorectal cancer: a multicenter, case-control, population-based study.Semantic proximity Read ↗

An intronic single nucleotide polymorphism in the MUTYH gene is associated with increased risk for HCV-induced hepatocellular carcinoma.Semantic proximity Read ↗

MYH mutations are rare in prostate cancer.Semantic proximity Read ↗

Exposing the MYtH about base excision repair and human inherited disease.Semantic proximity Read ↗

The MUTYH hotspot mutations p.G396D and p.Y179C do not cause substantial genetic susceptibility to biliary cancer.Semantic proximity Read ↗

A novel splice-site variant of the base excision repair gene MYH is associated with production of an aberrant mRNA transcript encoding a truncated MYH protein not localized in the nucleus.Semantic proximity Read ↗

Genetic alterations of the MYH gene in gastric cancer.Semantic proximity Read ↗

Oxidative DNA Damage and Human Cancer: Need for Cohort StudiesSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.