Article
Germline mutation prevalence in the base excision repair gene, MYH, in patients with endometrial cancer.
Clinical genetics - 1 Dec 2007
Barnetson R A, Devlin L, Miller J, Farrington S M, Slater S, Drake A C, Campbell H, Dunlop M G, Porteous M E
Abstract excerpt
Germline mutations in the base excision repair gene, MutY human homolog (MYH), have recently been associated with a recessively inherited multiple adenoma polyposis syndrome and colorectal cancer. The spectrum of extracolonic lesions is still being characterized, although preliminary reports suggest that bi-allelic mutation carriers may share some of the clinical features of other hereditary colon cancer...
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