Article
Proportion and phenotype of MYH-associated colorectal neoplasia in a population-based series of Finnish colorectal cancer patients.
The American journal of pathology - 1 Sept 2003
Enholm Susa, Hienonen Tuija, Suomalainen Anu, Lipton Lara, Tomlinson Ian, Kärjä Vesa, Eskelinen Matti, Mecklin Jukka-Pekka, Karhu Auli, Järvinen Heikki J, Aaltonen Lauri A
Abstract excerpt
Recessively inherited mutations in the base excision repair gene MYH have recently been associated with predisposition to colorectal adenomas and cancer in materials selected for occurrence of multiple adenomas. In particular, variants Y165C and G382D have been shown to play a role in Caucasian p...
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