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Article

Functional characterization of ABCC2 promoter polymorphisms and allele-specific expression.

The pharmacogenomics journal - 1 Oct 2013

Nguyen T D, Markova S, Liu W, Gow J M, Baldwin R M, Habashian M, Relling M V, Ratain M J, Kroetz D L

Abstract excerpt

Multidrug resistance protein 2 (MRP2, ABCC2) is an efflux membrane transporter highly expressed in liver, kidney and intestine with important physiological and pharmacological roles. The goal of this study was to investigate the functional significance of promoter region polymorphisms in ABCC2 and potential allele-specific expression. Twelve polymorphisms in the 1.6 kb region upstream of the translation start...

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Source

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Identifiers

PMID: 22664480
DOI: 10.1038/tpj.2012.20
PMCID: PMC3435480

Genes

ABCC2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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