Article
Polymorphisms in the ABCC2 (cMOAT/MRP2) gene found in 72 established cell lines derived from Japanese individuals: an association between single nucleotide polymorphisms in the 5'-untranslated region and exon 28.
Drug metabolism and disposition: the biological fate of chemicals - 1 Apr 2002
Itoda Masaya, Saito Yoshiro, Soyama Akiko, Saeki Mayumi, Murayama Norie, Ishida Seiichi, Sai Kimie, Nagano Michiyo, Suzuki Hiroshi, Sugiyama Yuichi, Ozawa Shogo, Sawada Ji Jun-ichi
Abstract excerpt
We found nucleotide variability in the 5'-upstream region and exonic sequences of a gene-encoding canalicular multispecific organic anion transporter/multidrug resistance-associated protein 2 (cMOAT/MRP2) by polymerase chain reaction-based sequencing using genomic DNA from 72 established cell lines derived from 72 Japanese individuals. Four single nucleotide polymorphisms (SNPs) were found in the...
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