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Article

Genetic variation and haplotype structure of the ABC transporter gene ABCG2 in a Japanese population.

Drug metabolism and pharmacokinetics - 1 Apr 2006

Maekawa Keiko, Itoda Masaya, Sai Kimie, Saito Yoshiro, Kaniwa Nahoko, Shirao Kuniaki, Hamaguchi Tetsuya, Kunitoh Hideo, Yamamoto Noboru, Tamura Tomohide, Minami Hironobu, Kubota Kaoru, Ohtsu Atsushi, Yoshida Teruhiko, Saijo Nagahiro, Kamatani Naoyuki, Ozawa Shogo, Sawada Jun-ichi

Abstract excerpt

The ATP-binding cassette transporter, ABCG2, which is expressed at high levels in the intestine and liver, functions as an efflux transporter for many drugs, including clinically used anticancer agents such as topotecan and the active metabolite of irinotecan (SN-38). In this study, to elucidate the linkage disequilibrium (LD) profiles and haplotype structures of ABCG2, we have comprehensively searched for...

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Share to ATP Binding Cassette Transporter, Subfamily G, Member 2
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 16702730
DOI: 10.2133/dmpk.21.109

Genes

ABCG2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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