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Identification of interleukin-6 promoter polymorphisms in the Chinese Han population and their functional significance*

30 Apr 2008

Abstract excerpt

OBJECTIVE: Interleukin-6 (IL-6) is a pivotal cytokine in both innate and adaptive immunity. Several polymorphisms in the IL-6 promoter have been reported in Western populations. However, little is known about their occurrence in the Chinese population. The functionality of IL-6 promoter polymorphisms remains controversial. DESIGN: Genetic, functional, and association studies. SETTING: National key laboratory of...

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PMID: 18434913
DOI: 10.1097/ccm.0b013e31816a0adb

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