Article
Interleukin 6 promoter polymorphisms in normal Han Chinese population: frequencies and effects on inflammatory markers.
Journal of investigative medicine : the official publication of the American Federation for Clinical Research - 1 Feb 2011
Pan Min, Gao Shu-Ping, Jiang Min-Hui, Guo Jing, Zheng Jin-Guo, Zhu Jian-Hua
Abstract excerpt
BACKGROUND: Interleukin 6 (IL-6) is a cytokine involved in different physiologic and pathophysiologic processes, and circulating levels of IL-6 differ greatly between individuals, but the results have not always been concordant among diverse populations. The aim of present study was to determine the prevalence of the 3 polymorphisms (-174G/C, -597G/A, and -634C/G) in the IL-6 gene promoter region and their...
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