Article
The association of functional polymorphisms of IL-6 gene promoter with ischemic stroke: analysis in two Chinese populations.
Biochemical and biophysical research communications - 1 Jan 2010
Tong Yeqing, Wang Zhihong, Geng Yijie, Liu Jianping, Zhang Renli, Lin Qiang, Li Xiaoheng, Huang Dana, Gao Shitong, Hu Dandan, Li Yongbin, Cheng Jinquan, Lu Zuxun
Abstract excerpt
Polymorphisms of G-572C and G-174C in the interleukin-6 (IL-6) promoter can affect both the transcription and secretion of IL-6 and may be involved in inflammation related to and the pathogenesis of ischemic stroke (IS). However, whether IL-6 polymorphisms are indeed risk factors for IS remains c...
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