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Article

Interleukin-6 -572C/G polymorphism is associated with serum interleukin-6 levels and risk of idiopathic pulmonary arterial hypertension.

Journal of the American Society of Hypertension : JASH - 1 Mar 2017

Fang Ming, Huang Yueye, Zhang Yuan, Ning Zhongping, Zhu Luoning, Li Xinming

Abstract excerpt

Interleukin 6 (IL-6) is a multifunctional proinflammatory cytokine that is elevated in patients with pulmonary arterial hypertension (PAH). Single nucleotide polymorphisms in the promoter region of IL-6 have been reported to transcriptional regulate the expression of IL-6. The aim of the present study is to investigate the roles of two common polymorphisms (-572C/G [rs1800796] and -6331T/C [rs10499563]) of IL-6...

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Share to Enzyme-Linked Immunosorbent Assay
Share to Familial Primary Pulmonary Hypertension
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Share to Promoter Regions, Genetic
Share to Sequence Analysis, DNA

Source

Identifiers

PMID: 28229900
DOI: 10.1016/j.jash.2017.01.011

Genes

PAH

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

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