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Article

Association between Interleukin-6 Promoter Polymorphism (-174 G/C), Serum Interleukin-6 Levels and Mortality in Severe Septic Patients.

International journal of molecular sciences - 8 Nov 2016

Lorente Leonardo, Martín María M, Pérez-Cejas Antonia, Barrios Ysamar, Solé-Violán Jordi, Ferreres José, Labarta Lorenzo, Díaz César, Jiménez Alejandro

Abstract excerpt

The association between interleukin (IL)-6 promoter polymorphism (-174 G/C), circulating IL-6 levels and mortality in septic patients has scarcely been addressed, and then only in studies of small sample size, and a direct association among them has not been previously reported. Therefore, the purpose of our study was to determine whether this association exists. An observational, prospective and multicenter...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 27834822
DOI: 10.3390/ijms17111861
PMCID: PMC5133861

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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