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Article

IL6 gene-wide haplotype is associated with susceptibility to acute lung injury.

Translational research : the journal of laboratory and clinical medicine - 1 Jul 2008

Flores Carlos, Ma Shwu-Fan, Maresso Karen, Wade Michael S, Villar Jesus, Garcia Joe G N

Abstract excerpt

Experimental and clinical studies support the key role of interleukin 6 (IL-6), a potent proinflammatory cytokine, in the development of acute lung injury (ALI). Plasma IL-6 levels are influenced mainly by genetic determinants, and a -174G/C polymorphism of the gene has been recently associated with susceptibility to ALI. Here we aimed to validate the association of the IL6 gene with ALI in a case-control sample...

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Identifiers

PMID: 18593632
DOI: 10.1016/j.trsl.2008.05.006

Genes

IL6

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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