Article
Statistical analysis of fitness data determined by TAG hybridization on microarrays.
Methods in molecular biology (Clifton, N.J.) - 1 Jan 2008
Peyser Brian D, Irizarry Rafael, Spencer Forrest A
Abstract excerpt
TAG, or bar-code, microarrays allow measurement of the oligonucleotide sequences (TAGs) that mark each strain of deletion mutants in the Saccharomyces cerevisiae yeast knockout (YKO) collection. Comparison of genomic DNA from pooled YKO samples allows estimation of relative abundance of TAGs marking each deletion strain. Features of TAG hybridizations create unique challenges for analysis. Analysis is complicated...
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