Article
Improved microarray methods for profiling the Yeast Knockout strain collection.
Nucleic acids research - 1 Jul 2005
Yuan Daniel S, Pan Xuewen, Ooi Siew Loon, Peyser Brian D, Spencer Forrest A, Irizarry Rafael A, Boeke Jef D
Abstract excerpt
A remarkable feature of the Yeast Knockout strain collection is the presence of two unique 20mer TAG sequences in almost every strain. In principle, the relative abundances of strains in a complex mixture can be profiled swiftly and quantitatively by amplifying these sequences and hybridizing them to microarrays, but TAG microarrays have not been widely used. Here, we introduce a TAG microarray design with...
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