Article
Simultaneous genotyping, gene-expression measurement, and detection of allele-specific expression with oligonucleotide arrays.
Genome research - 1 Feb 2005
Ronald James, Akey Joshua M, Whittle Jacqueline, Smith Erin N, Yvert Gael, Kruglyak Leonid
Abstract excerpt
Oligonucleotide microarrays provide a high-throughput method for exploring genomes. In addition to their utility for gene-expression analysis, oligonucleotide-expression arrays have also been used to perform genotyping on genomic DNA. Here, we show that in segregants from a cross between two unrelated strains of Saccharomyces cerevisiae, high-quality genotype data can also be obtained when mRNA is hybridized to...
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