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Article

Quantitative phenotypic analysis of yeast deletion mutants using a highly parallel molecular bar-coding strategy.

Nature genetics - 1 Dec 1996

Shoemaker D D, Lashkari D A, Morris D, Mittmann M, Davis R W

Abstract excerpt

A quantitative and highly parallel method for analysing deletion mutants has been developed to aid in determining the biological function of thousands of newly identified open reading frames (ORFs) in Saccharomyces cerevisiae. This approach uses a PCR targeting strategy to generate large numbers of deletion strains. Each deletion strain is labelled with a unique 20-base tag sequence that can be detected by...

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PMID: 8944025
DOI: 10.1038/ng1296-450

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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