Article
Competition experiments coupled with high-throughput analyses for functional genomics studies in yeast.
Methods in molecular biology (Clifton, N.J.) - 1 Jan 2011
Delneri Daniela
Abstract excerpt
Competition experiments are an effective way to provide a measurement of the fitness of yeast strains. The availability of the Saccharomyces cerevisiae yeast knock-out (YKO) deletion collection allows scientists to retrieve fitness data for the ~6,000 S. cerevisiae genes at the same time in a given environment. The molecular barcodes, characterizing each yeast mutant, serve as strain identifiers, which can be...
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