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Article

Sequence editing by Apolipoprotein B RNA-editing catalytic component [corrected] and epidemiological surveillance of transmitted HIV-1 drug resistance.

AIDS (London, England) - 30 Mar 2008

Gifford Robert J, Rhee Soo-Yon, Eriksson Nicolas, Liu Tommy F, Kiuchi Mark, Das Amar K, Shafer Robert W

Abstract excerpt

DESIGN: Promiscuous guanine (G) to adenine (A) substitutions catalysed by apolipoprotein B RNA-editing catalytic component (APOBEC) enzymes are observed in a proportion of HIV-1 sequences in vivo and can introduce artifacts into some genetic analyses. The potential impact of undetected lethal editing on genotypic estimation of transmitted drug resistance was assessed. METHODS: Classifiers of lethal,...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 18356601
DOI: 10.1097/QAD.0b013e3282f5e07a
PMCID: PMC2946849

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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