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Article

Human APOBEC3 proteins, retrovirus restriction, and HIV drug resistance.

AIDS reviews - 1 Jan 2000

Haché Guylaine, Mansky Louis M, Harris Reuben S

Abstract excerpt

Over 40 million people worldwide currently have HIV/AIDS. Many antiretroviral drugs have proven effective, but drug-resistant HIV variants frequently emerge to thwart treatment efforts. Reverse transcription errors undoubtedly contribute to drug resistance, but additional significant sources of viral genetic variation are debatable. The human APOBEC3F and APOBEC3G proteins can potently inhibit retrovirus...

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Identifiers

PMID: 17078485

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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