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Article

Mapping protease inhibitor resistance to human immunodeficiency virus type 1 sequence polymorphisms within patients.

Journal of virology - 1 Dec 2007

Poon Art F Y, Kosakovsky Pond Sergei L, Richman Douglas D, Frost Simon D W

Abstract excerpt

Resistance genotyping provides an important resource for the clinical management of patients infected with human immunodeficiency virus type 1 (HIV-1). However, resistance to protease (PR) inhibitors (PIs) is a complex phenotype shaped by interactions among nearly half of the residues in HIV-1 PR. Previous studies of the genetic basis of PI resistance focused on fixed substitutions among populations of HIV-1,...

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Identifiers

PMID: 17913806
DOI: 10.1128/JVI.01570-07
PMCID: PMC2168824

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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