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Article

HIV-1 Protease, Reverse Transcriptase, and Integrase Variation.

Journal of virology - 1 Jul 2016

Rhee Soo-Yon, Sankaran Kris, Varghese Vici, Winters Mark A, Hurt Christopher B, Eron Joseph J, Parkin Neil, Holmes Susan P, Holodniy Mark, Shafer Robert W

Abstract excerpt

UNLABELLED: HIV-1 protease (PR), reverse transcriptase (RT), and integrase (IN) variability presents a challenge to laboratories performing genotypic resistance testing. This challenge will grow with increased sequencing of samples enriched for proviral DNA such as dried blood spots and increased use of next-generation sequencing (NGS) to detect low-abundance HIV-1 variants. We analyzed PR and RT sequences from...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Identifiers

PMID: 27099321
DOI: 10.1128/JVI.00495-16
PMCID: PMC4907232

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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