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Article

Temporal trend of drug-resistance and APOBEC editing in PBMC genotypic resistance tests from HIV-1 infected virologically suppressed individuals.

Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology - 1 Nov 2023

Armenia D, Gagliardini R, Alteri C, Svicher V, Cento V, Borghi V, Vergori A, Cicalini S, Forbici F, Fabeni L, Bertoli A, Brugneti M, Gennari W, Malagnino V, Andreoni M, Mussini C, Antinori A, Perno C F, Santoro M M, Ceccherini-Silberstein F

Abstract excerpt

BACKGROUND: We aimed at evaluating the temporal trend of drug-resistance and APOBEC editing from HIV-DNA genotypic resistance tests (GRT) in virologically suppressed individuals. MATERIAL AND METHODS: Major resistance mutations (MRM), genotypic susceptibility score (GSS) for the current regimen and APOBEC-related mutations (APO-M) were evaluated. Potential changes in trends of MRM and APO-M over-time were...

Topics

Humans
HIV Infections
HIV-1
Drug Resistance, Viral
Male
Female
Adult
Genotype
Anti-HIV Agents
APOBEC Deaminases

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Leukocytes, Mononuclear

Middle Aged

Mutation

Source

Identifiers

PMID: 37573167
DOI: 10.1016/j.jcv.2023.105551

Genes

GSS

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026.

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