Article
Family-based association analyses of alcohol dependence phenotypes across DRD2 and neighboring gene ANKK1.
Alcoholism, clinical and experimental research - 1 Oct 2007
Dick Danielle M, Wang Jen C, Plunkett Jevon, Aliev Fazil, Hinrichs Anthony, Bertelsen Sarah, Budde John P, Goldstein Elianna L, Kaplan Daniel, Edenberg Howard J, Nurnberger John, Hesselbrock Victor, Schuckit Marc, Kuperman Sam, Tischfield Jay, Porjesz Bernice, Begleiter Henri, Bierut Laura Jean, Goate Alison
Abstract excerpt
BACKGROUND: There is an extensive and inconsistent literature on the association of the dopamine D2 receptor gene (DRD2) with alcohol dependence. Conflicting results have been attributed to differences in the severity of the alcohol dependence phenotype across studies, failure to exclude related disorders from comparison groups, and artifacts of population-stratification. Recently the genetic polymorphism most...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.