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Article

A DRD2 and ANKK1 haplotype is associated with nicotine dependence.

Psychiatry research - 30 Apr 2012

Voisey Joanne, Swagell Christopher Dean, Hughes Ian Paul, van Daal Angela, Noble Ernest Pascal, Lawford Bruce Robert, Young Ross McDonald, Morris Charles Phillip

Abstract excerpt

To test the importance of the dopamine D2 receptor (DRD2) region in nicotine dependence, 150 smokers and 228 controls were genotyped for the DRD2 C957T, -141delC and ANKK1 TaqIA polymorphisms (rs6277, rs1799732 and rs1800497, respectively). The -141delC SNP did not show any association but both the C957T and TaqIA SNPs showed association at the allele, genotype, haplotype and combined genotype levels. The...

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Share to Chi-Square Distribution
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Share to Genetic Predisposition to Disease
Share to Polymorphism, Genetic
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Share to Receptors, Dopamine D2
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Source

Identifiers

PMID: 22382052
DOI: 10.1016/j.psychres.2011.09.024

Genes

DRD2

Variants

rs6277

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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