Article
Association of specific haplotypes of neurotrophic tyrosine kinase receptor 2 gene (NTRK2) with vulnerability to nicotine dependence in African-Americans and European-Americans.
Biological psychiatry - 1 Jan 2007
Beuten Joke, Ma Jennie Z, Payne Thomas J, Dupont Randolph T, Lou Xiang-Yang, Crews Karen M, Elston Robert C, Li Ming D
Abstract excerpt
BACKGROUND: The gene encoding neurotrophic tyrosine kinase receptor 2 (NTRK2) has been localized to a region on chromosome 9q22-q23 that showed a "suggestive" linkage to nicotine dependence (ND) in our previous linkage analyses. However, no association of NTRK2 with ND has been identified. METHODS: Family-based association analyses of 2037 participants (1366 African Americans [AA], 671 European Americans [EA])...
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