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Article

Two cell lineages, myf5 and myf5-independent, participate in mouse skeletal myogenesis.

Developmental cell - 1 Mar 2008

Haldar Malay, Karan Goutam, Tvrdik Petr, Capecchi Mario R

Abstract excerpt

In skeletal muscle development, the myogenic regulatory factors myf5 and myoD play redundant roles in the specification and maintenance of myoblasts, whereas myf6 has a downstream role in differentiating myocytes and myofibers. It is not clear whether the redundancy between myf5 and myoD is within the same cell lineage or between distinct lineages. Using lineage tracing and conditional cell ablation in mice, we...

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Source

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Identifiers

PMID: 18331721
DOI: 10.1016/j.devcel.2008.01.002
PMCID: PMC2917991

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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