Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Different autonomous myogenic cell populations revealed by ablation of Myf5-expressing cells during mouse embryogenesis.

Development (Cambridge, England) - 1 May 2008

Gensch Nicole, Borchardt Thilo, Schneider Andre, Riethmacher Dieter, Braun Thomas

Abstract excerpt

The development of myogenic cells is mainly determined by expression of two myogenic factors, Myf5 and Myod1 (MyoD), which genetically compensate for each other during embryogenesis. Here, we demonstrate by conditional cell ablation in mice that Myf5 determines a distinct myogenic cell population, which also contains some Myod1-positive cells. Ablation of this lineage uncovers the presence of a second autonomous...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Animals, Newborn
Share to Bone and Bones

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Cell Lineage

Share to Mesenchymal Stem Cells

Share to Muscle Development

Share to Myoblasts, Skeletal

Share to MyoD Protein

Share to Myogenic Regulatory Factor 5

Source

Identifiers

PMID: 18367555
DOI: 10.1242/dev.019331

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Different autonomous myogenic cell populations revealed by ablation of Myf5-expressing cells during mouse embryogenesis.PMID 18367555Read ↗

Two cell lineages, myf5 and myf5-independent, participate in mouse skeletal myogenesis.Semantic proximity Read ↗

Targeted inactivation of myogenic factor genes reveals their role during mouse myogenesis: a review.Semantic proximity Read ↗

Myf-5 and myoD genes are activated in distinct mesenchymal stem cells and determine different skeletal muscle cell lineages.Semantic proximity Read ↗

ES-cells carrying two inactivated myf-5 alleles form skeletal muscle cells: activation of an alternative myf-5-independent differentiation pathway.Semantic proximity Read ↗

Mrf4 determines skeletal muscle identity in Myf5:Myod double-mutant mice.Semantic proximity Read ↗

MyoD or Myf-5 is required for the formation of skeletal muscle.Semantic proximity Read ↗

Myogenin can substitute for Myf5 in promoting myogenesis but less efficiently.Semantic proximity Read ↗

Cultured myf5 null and myoD null muscle precursor cells display distinct growth defects.Semantic proximity Read ↗

The multifaceted role of MyoD in adult skeletal muscle: homeostasis, regeneration, and diseasesSemantic proximity Read ↗

Dlk1 Is Necessary for Proper Skeletal Muscle Development and RegenerationSemantic proximity Read ↗

Muscle deficiency and neonatal death in mice with a targeted mutation in the myogenin gene.Semantic proximity Read ↗

Skeletal muscle phenotypes initiated by ectopic MyoD in transgenic mouse heart.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.