Article
Development and patterning of rib primordia are dependent on associated musculature.
Developmental biology - 1 Dec 2020
Wood William M, Otis Chelsea, Etemad Shervin, Goldhamer David J
Abstract excerpt
The importance of skeletal muscle for rib development and patterning in the mouse embryo has not been resolved, largely because different experimental approaches have yielded disparate results. In this study, we utilize both gene knockouts and muscle cell ablation approaches to re-visit the extent to which rib growth and patterning are dependent on developing musculature. Consistent with previous studies, we show...
Topics
- Alleles
- Animals
- Body Patterning
- Gonadotropin-Releasing Hormone
- Mice, Transgenic
- Muscle, Skeletal
- MyoD Protein
- Myogenic Regulatory Factor 5
- Myogenic Regulatory Factors
- Ribs