Myogenin can substitute for Myf5 in promoting myogenesis but less efficiently.

doi:10.1242/dev.124.13.2507

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Article

Myogenin can substitute for Myf5 in promoting myogenesis but less efficiently.

Development (Cambridge, England) - 1 Jul 1997

Wang Y, Jaenisch R

Abstract excerpt

The myogenic basic Helix-Loop-Helix transcription factors, including Myf5, MyoD, myogenin (myg) and MRF4, play important roles in skeletal muscle development. The phenotypes of mutant mice deficient in either gene are different, suggesting that each gene may have a unique function in vivo. We pre...

Topics

Alleles
Animals
Crosses, Genetic
DNA-Binding Proteins
Genes, Lethal
Helix-Loop-Helix Motifs
Mice
Mice, Mutant Strains
Morphogenesis
Muscle Proteins
Muscle, Skeletal
MyoD Protein
Myogenic Regulatory Factor 5
Myogenin
Phenotype
Trans-Activators
Transcription Factors

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