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Article

Inducible Expression of Cre Recombinase in the Retinal Pigmented Epithelium

1 Mar 2008

Abstract excerpt

PURPOSE: The retinal pigmented epithelium (RPE) expresses many genes that play important roles in the support and maintenance of photoreceptors. The present study was conducted to develop a system amenable to the dissection of the temporal function of these genes, specifically within RPE cells. Transgenic mice were generated and characterized in which the expression of Cre recombinase could be specifically...

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PMID: 18326755
DOI: 10.1167/iovs.07-1105

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