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Article

Transplantation of reprogrammed embryonic stem cells improves visual function in a mouse model for retinitis pigmentosa.

Transplantation - 27 Apr 2010

Wang Nan-Kai, Tosi Joaquin, Kasanuki Jennifer Mie, Chou Chai Lin, Kong Jian, Parmalee Nancy, Wert Katherine J, Allikmets Rando, Lai Chi-Chun, Chien Chung-Liang, Nagasaki Takayuki, Lin Chyuan-Sheng, Tsang Stephen H

Abstract excerpt

BACKGROUND: To study whether C57BL/6J-Tyr/J (C2J) mouse embryonic stem (ES) cells can differentiate into retinal pigment epithelial (RPE) cells in vitro and then restore retinal function in a model for retinitis pigmentosa: Rpe65/Rpe65 C57BL6 mice. METHODS: Yellow fluorescent protein (YFP)-labele...

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Identifiers

PMID: 20164818
DOI: 10.1097/TP.0b013e3181d45a61
PMCID: PMC2855750

Genes

RPE

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-20164818-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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