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Article

Pou4f2 knock-in Cre mouse: A multifaceted genetic tool for vision researchers.

Molecular vision - 1 Jan 2016

Simmons Aaron B, Bloomsburg Samuel J, Billingslea Samuel A, Merrill Morgan M, Li Shuai, Thomas Marshall W, Fuerst Peter G

Abstract excerpt

PURPOSE: A transgenic mouse that expresses Cre recombinase under control of the Pou4f2-promoter (also referred to as Brn-3b and Brn-3.2) was characterized. Pou4f2 expression has been reported in a subset of retinal ganglion cells (RGCs) in the retina, in the midbrain, and in the germline. In this study, we characterize the expression pattern of this Cre-recombinase line and report its utility in targeted...

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PMID: 27390513
PMCID: PMC4919092

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Source receipt: pubmed, retrieved 7 Sept 2026.

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