Article
Increased transgene expression by the mouse tyrosinase enhancer is restricted to neural crest-derived pigment cells.
Genesis (New York, N.Y. : 2000) - 1 Apr 2001
Camacho-Hübner A, Beermann F
Abstract excerpt
In this study, we have addressed the impact of the mouse tyrosinase enhancer on regulated expression from the mouse tyrosinase promoter during embryonic development. Stable and transient transgenic experiments using the reporter gene lacZ reveal that (1) expression is detected in neural crest-derived melanoblasts from E11.5 onward, (2) the enhancer does not increase transgenic expression in optic cup-derived...
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